Cialis, like all medications, may cause undesirable effects. The extent of these effects or the duration may differ from person to person, due to various factors. It is wrong to assume that everyone who takes Cialis will experience side effects. A large number of users will not have any undesirable effects of the drug. Here is a look at answers to the question what should I not take with Cialis? This answer with reasons for the effects helps to deal with the effects.
The link between mechanism of action and Cialis side effects
Certain effects are the result of the way Cialis works. For instance, Cialis prevents an enzyme that is responsible for the breakdown of cGMP in the smooth muscle cells of the penis and blood vessels. This helps relax the smooth muscles and increases blood flow. As a result, the penis achieves and maintain an erection when sexually stimulated.
When sexually stimulated, the nerves release nitric oxide (NO) in the penile tissues. This results in the production of cGMP. Cialis ensures that cGMP level is maintained, resulting in a stronger erection for a longer time.
Here is a quick look at some of the mild side effects of Cialis and the direct link to how Cialis works:
- Cialis may cause headache. This is due to the vasodilatory effects of the drug, that result in increased blood flow and pressure in the head.
- Due to smooth muscle relaxation in the digestive tract, gastrointestinal symptoms may be experienced. As a result, there is a possibility of indigestion and heartburn.
- Skin flushing or a warm sensation in the upper part of the body is due to the vasodilatory properties.
- Due to muscle-relaxing effects of Cialis, back pain and pain in the muscles are also possible.
- Nasal congestion is due to the increased blood flow in the blood vessels in the nasal passages.
In addition to the above, there are also possible serious side effects of Cialis. These effects are relatively rare, and may be experienced only by a section of users. However, everyone needs to be aware of these possible effects, and identify the symptoms.
#1 Vision impact - In rare cases, Cialis may cause effects on vision. This includes changes in color vision or sensitivity to light. This is a serious condition and requires immediate medical attention.
#2 Priapism – This refers to a long and painful erection that lasts for more than four hours. In such instances, urgent medical attention is required. This is to prevent any possible permanent damage to the penile tissues.
Cialis side effects long-term
Cialis is considered to be well-tolerated. However, certain long term effects are likely to be experienced. These effects are a common result of long term use of medications. The possibility of these effects depend on many factors.
#1 Long-term use may result in a reduced response to the medication, requiring higher dosages.
#2 Continuous use may result in psychological dependence.
#3 A mild decrease in blood pressure is possible with long term use.
#4 Sudden loss of hearing is also possible with long term Cialis use.
#5 Due to drug interactions, it may affect use of other drugs taken on a long term basis.
#6 There is a possibility of effects on sperm quality and fertility. However, this needs to be studied further.
What should I not take with Cialis?
Ensure that Cialis is not taken along with the type of medications shown in the list below. Sometimes, doctors may prescribe alternate medications, or may change dosages. Doctors also recommend taking the medications with a gap between different drugs. Here is a list of the type of drugs that may interact with Cialis:
- Nitrates - Cialis when taken along with nitrates can cause a big drop in blood pressure.
- Alpha-Blockers - When taken with Cialis, can decrease blood pressure.
- Other PDE5 Inhibitors – When taken with other PDE5 inhibitors Cialis can increase the risk of side effects.
- Antibiotics – Medications like erythromycin and clarithromycin can increase the drug levels of Cialis, with more risk of side effects.
- Antifungal Medications - Drugs like ketoconazole and itraconazole can also increase the risk of side effects of Cialis.
- HIV Medications – Drugs such as ritonavir and saquinavir, can increase the blood levels of Cialis. As a result of this, there could be a higher risk of serious effects.
Tips on avoiding Cialis side effects
As explained, unwanted effects are due to:
- The way Cialis works
- Wrong dosage
- Wrong time of intake
- Drug interactions
- Existing health conditions
To avoid possible side effects, the best option is to check for any existing health conditions and take treatment. Also, ensure that Cialis is taken in the right dosage and at the right time. Finally, follow recommendations to avoid drug interactions.